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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCH2 All Species: 19.09
Human Site: S1147 Identified Species: 42
UniProt: O75038 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75038 NP_055453.2 1416 154668 S1147 R D S V S S S S S M S S S D T
Chimpanzee Pan troglodytes XP_001149239 1685 188441 A1190 E P G S S I S A L I G Q F D E
Rhesus Macaque Macaca mulatta XP_001085424 1423 155915 S1154 R D S V S S S S S M S S S D T
Dog Lupus familis XP_546733 1387 151432 S1132 R D S V S S S S S V S S S D T
Cat Felis silvestris
Mouse Mus musculus A2AP18 1501 164279 S1232 R D S V S S S S S M S S N D T
Rat Rattus norvegicus Q62688 1096 122754 S852 H I A I T N R S G G G K A Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q2VRL0 637 72514 E393 S E K F V S F E H S L A H Q K
Frog Xenopus laevis Q32NH8 758 87399 S514 H Y I L Y E M S S V T E Y K A
Zebra Danio Brachydanio rerio A5D6R3 784 89362 A540 T S F S E N E A L K L I K D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25455 1318 146373 E1074 P H S E P G V E I P A C P L D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783611 2724 302530 S1491 M G N P S K F S S C N G N N D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.4 94 78.7 N.A. 77.2 21.2 N.A. N.A. 21.2 24.7 24.5 N.A. 24.2 N.A. N.A. 26.4
Protein Similarity: 100 59.9 95.4 82.9 N.A. 81.6 36.7 N.A. N.A. 30.7 35.3 35 N.A. 40.3 N.A. N.A. 35.7
P-Site Identity: 100 20 100 93.3 N.A. 93.3 6.6 N.A. N.A. 6.6 13.3 6.6 N.A. 6.6 N.A. N.A. 20
P-Site Similarity: 100 33.3 100 100 N.A. 100 40 N.A. N.A. 20 33.3 26.6 N.A. 13.3 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 19 0 0 10 10 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % C
% Asp: 0 37 0 0 0 0 0 0 0 0 0 0 0 55 19 % D
% Glu: 10 10 0 10 10 10 10 19 0 0 0 10 0 0 10 % E
% Phe: 0 0 10 10 0 0 19 0 0 0 0 0 10 0 0 % F
% Gly: 0 10 10 0 0 10 0 0 10 10 19 10 0 0 0 % G
% His: 19 10 0 0 0 0 0 0 10 0 0 0 10 0 0 % H
% Ile: 0 10 10 10 0 10 0 0 10 10 0 10 0 0 0 % I
% Lys: 0 0 10 0 0 10 0 0 0 10 0 10 10 10 19 % K
% Leu: 0 0 0 10 0 0 0 0 19 0 19 0 0 10 0 % L
% Met: 10 0 0 0 0 0 10 0 0 28 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 19 0 0 0 0 10 0 19 10 0 % N
% Pro: 10 10 0 10 10 0 0 0 0 10 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 19 0 % Q
% Arg: 37 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % R
% Ser: 10 10 46 19 55 46 46 64 55 10 37 37 28 0 10 % S
% Thr: 10 0 0 0 10 0 0 0 0 0 10 0 0 0 37 % T
% Val: 0 0 0 37 10 0 10 0 0 19 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 10 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _